摘要
本工作在大鼠离体脊髓缺氧－复氧损伤模型上，观察了脊髓组织牛磺酸转运的特征，结果发现：缺氧４５ｍｉｎ后复氧孵育１５ｍｉｎ，脊髓组织出现明显的牛磺酸转运的障碍，表现为Ｖ＿（ｍａｘ）明显降低（为正常组的７１％，Ｐ＜０．０１），Ｋｍ值无明显改变，推测缺氧。复氧可能通过影响能量代谢而导致脊髓组织牛磺酸转运的障碍。
he characteristics of taurine transfer was investigated on anoxia-reoxygenation model ofisolated rat spinal cord.The results showed after 45 min anoxia and 15 min reoxygenation,taurinetransfer of spinal cord was significantly reduced,it manifested that Vmax decreased(71%of con-trol,P<0. 01),Km was not changed.It mdwy be infered that anoxia-reoxygenation decreases thetransfer of spinal cord through dysfunction of energy metabolism.
出处
《基础医学与临床》
CSCD
1996年第5期364-366,共3页
Basic and Clinical Medicine
关键词
缺氧
复氧
脊髓损伤
anoxia-reoxygenation spinal cord taurine transfer
