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降脂药对高脂血症大鼠血液粘度及红细胞膜流动性的影响 被引量:2

Effect of Some Drugs on the Blood Lipids,Blood Viscosity and RBC Membrane Fluiditv in Rat with Hyperlipidemia
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摘要 观察实验性高脂血症大鼠血液粘度及红细胞膜流动性的改变。结果表明,高脂血症大鼠血浆粘度明显增高,红细胞膜流动性减小。使用中药降脂健心冲剂和氯贝丁脂(冠心平),不仅有降低血脂浓度作用,而且对血液粘度和膜流动性的复原有好处。 model of rat hyperlipidemia was made using fed high lipidic foods for 15 days. The total choleterol(TC),triglycerid(TG).HDL-choleterol(HDL-C),LDL-choleterol(LDL-C),blood vis-cosity and RBC membrane fluidity were determined.The results showed that the plasma viscosity and RBC membrane lipids microviscosity increased significantly with the increase of TC,TG. The treatment with chofibrate and Chinese drug inhibited markedly these changes,indicating both drugs can reduce blood viscosity and RBC membrane lipids microviscosity as well as reduce TC,TG in rat with hyperlipidemia。
出处 《基础医学与临床》 CSCD 1996年第4期309-311,共3页 Basic and Clinical Medicine
关键词 高脂血症 血液粘度 红细胞膜流动性 降脂药 hyperlipidemia vlood viscosity membrane fluidity chofibrate chinese drugX
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