1Weiss JM, Nath A, Major EO, et al. HIV-1 Tat induces monocyte chemoattractant protein-l-mediated monocyte transmigration across a model of the human blood-brain barrier and up-regulates CCR5 expression on human monocytes[ J]. J Immunol, 1999,163 ( 5 ) :2953-2959.
2Bowman T, Garcia R, Turkson J, et al. STATs in oncogenesis[J]. Oncogene, 2000, 19(21) :2474-2488.
3Grandis JR, Drenning SD, Zeng Q, et al. Constitutive activation of STAT3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo [ J ]. Proc Natl Acad Sci USA, 2000, 97 (8):4227 -4232.
4Schuringa JJ, Wierenga AT, Knfijer W, et al. Constitutive STAT3,Tyr705, and Ser727 phosphorylation in acute myeloid leukemia cells caused by the autocrine secretion of interleukin-6 [ J ].Blood, 2000, 95(12) :3765-3770.
5Badache A, Hynes NE. Interleukin 6 inhibits proliferation and,in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells [ J ]. CancerRes, 2001,61 ( 1 ) :383-391.
6Buettner R, Mora LB, Jove R. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention[J]. Clin Cancer Res, 2002, 8(4) :945-954.
7Bromberg JF, Horvath CM, Besser D, et al. STAT3 activation is required for cellular transformation by v-src [ J ]. Mol Cell Biol,1998, 18(5) :2553-2558.
8Leong PL, Andrews GA, Johnson DE, et al. Targeted inhibition of STAT3 with a decoy oligonucleotide abrogates head and neck cancer cell growth[J]. Proc Natl Acad Sci USA, 2003,100(7) :4138-4143.
9Huang JS, Guh JY, Hung WC, et al. Role of the Janus kinase(JAK)/signal transducers and activators of transcription (STAT)cascade in advanced glycation end-product-induced cellular mitogenesisNRK-49F cells [J]. Biochem J, 1999, 342( pt 1 ) :231-238.
10Sui G, Soohoo C, Affarel B, et al. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells [ J ].Proc Natl Acad Sci USA, 16, 2002 ,99(8) :5515-5520.
