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胰岛素治疗46例2型糖尿病临床分析

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摘要 目的观察胰岛素治疗对2型糖尿病患者血糖控制的效果。方法:对46例2型糖尿病患者短期皮下注射胰岛素强化治疗后继续胰岛素联合口服降糖药物治疗,边用药、边监测血糖,观察用药7—14天,并跟踪半年。结果血糖达到理想控制状态,胰岛素治疗后患者的空腹血糖、餐后2小时血糖、HbA1C明显低于治疗前,P<0.01。其中7例只需饮食、运动治疗便可获得良好的血糖控制。结论2型糖尿病患者在糖尿病教育、饮食控制、运动疗法、监测血糖的基础上,通过适当的胰岛素治疗,其病情均可得到良好的控制,并保护健存的胰岛B细胞功能,且副作用轻微。
出处 《医学信息(西安上半月)》 2006年第12期2167-2169,共3页 Medical Information
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  • 1Peter P, Frank R, Nick G, et al. Sulfonylurea stimulation of in aulin secretion. Diabetes, 2002,51 ( Suppl 3): S368-S376.
  • 2Garratt KN, Brady PA, Haasinger NL, et al. Sulfonylurea drugs increase early motality in patients with diabetes mellitus after direct angioplasty for acute myocardial infaction. J Am Cell Cardiol, 1999,33:119-124.
  • 3Matthaei S, Stumvoll M, Kellerer M, et al. Pathophysiology and pharmacological treatment of insulin resistance. Endocr Rev,2000,21:585-618.
  • 4Davis TM, Parsons RW, Broadburst R J, et al. Arrhythmias and mortality after myocardial infaction in diabetic patients: relationship to diabetes treatment. Diabetes Care, 1998,21:637-640.
  • 5Renstrom E, Barg S, Thevenod F, et al. Sul.fonylurea-mediated stimulation of insulin exocytosis via an ATP-sensitive K + channel-independent action. Diabetes, 2002,51 (Suppl 1 ): S33-S36.
  • 6Muller G. The molecular mechanism of the insulin-mimetic/sensitizing activity of the antidiabetic suffonylurea drug Amaryl. Mol Med, 2000,6:907-933.
  • 7Dills DG, Schneider J. Glimepiride/Glyburide Research Group. Clinical evaluation of glimepiride versus glyburide in NIDDM in a double-blind comparative study. Horm Metab Res, 1996,28:426-429.
  • 8Muller G. Dynamics of plasma membrane microdomains and cross-talk to the insulin signalling cascade. FEBS Lett, 2002,531: 81-87.
  • 9DeFronzo RA. Pharmacologic therapy for type 2 diabetes mellitus. Ann Intern Med, 1999,131:281-303.
  • 10Richard A, Michelle S, Phillip B. Oral agents for the treatment of type 2diabetes mellitus: pharmacology, toxicity, and treatment. Ann Emeg Med,2001,38:68-78.

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