期刊文献+

系统性红斑狼疮和梅毒患者抗磷脂抗体比较及意义 被引量:1

原文传递
导出
摘要 目的:比较系统性红斑狼疮(SLE)和梅毒患者血清抗磷脂抗体(APA)的异同及其意义。方法:应用ELISA和快速血浆反应素环状卡片试验(RPR)法检测32例SLE和77例梅毒患者血中6种抗心磷脂(CL)、抗磷脂酸(PA)、抗磷脂酰丝氨酸(PS)、抗磷脂酰乙醇胺(PE)、抗磷脂酰胆碱(PC)、抗磷脂酰肌醇抗体(PI)的APA。结果:(1)梅毒患者血清RPR的滴度为1∶16、1∶8和1∶1(抗PE抗体除外)及RPR的滴度为1∶4的6种APAIgG的吸光度(A)值,以及RPR的滴度为1∶1的抗PAIgG抗体、滴度为1∶8的抗PCIgG抗体和滴度为1∶32、1∶16及1∶8的抗PIIgG抗体的阳性率,均显著低于SLE患者;(2)梅毒患者血清RPR的滴度为1∶4的4种APAIgM和滴度为1∶1的5种APAIgM的A值,以及RPR滴度为1∶1梅毒患者抗CL、抗PS和抗PCIgM抗体及滴度为1∶32的抗PAIgM的阳性率,均显著低于SLE患者。结论:SLE和梅毒患者血清的A值和阳性率均有所不同,检测A值有助于SLE与梅毒患者的鉴别。
出处 《细胞与分子免疫学杂志》 CAS CSCD 北大核心 2006年第6期772-773,776,共3页 Chinese Journal of Cellular and Molecular Immunology
  • 相关文献

参考文献5

  • 1贾杰芳,杨文东,马庆海.SLE、RA患者血清sICAM-1和PTM水平的变化及其临床意义[J].细胞与分子免疫学杂志,2003,19(2):203-204. 被引量:6
  • 2Gibson GE,Su WP,Pittelkow MR.Antiphospholipid syndrome and the skin[J].J Amer Acad Derm,1997,36(6):970-982.
  • 3张奉春,田新平.抗磷脂综合征*风湿病学[M].北京:科学出版社,1995:1547-1561.
  • 4Michael D,Lockshin MD.Which patients with antiphospholioid antibody should be treated and how?[J].Contro Clin Rhrum,1993,19 (1):235-247.
  • 5Levine JS,Branch DW,Rauch J.The Antiphospholipid Syndrome[J].New Eng J Med,2002,346 (10):752-763.

二级参考文献4

共引文献5

同被引文献19

  • 1Reddy P. Laboratory diagnosis of antiphospholipid syndrome[J].{H}Southern Medical Journal,2013,(07):439-446.
  • 2Chiu YE,Co DO. Juvenile dermatomyositis:immunopathogenesis,role of myositis-specific autoantibodies,and review of rituximab use[J].{H}Pediatric Dermatology,2011,(04):357-367.
  • 3Pons-Estel GJ,Salemi GE,Serrano RM. Therapeutic plasma exchange for the management of refractory systemic autoimmune diseases:report of 31 cases and review of the literature[J].{H}Autoimmunity Reviews,2011,(11):679-684.
  • 4Broccolo F,Drago F,Cassina G. Selective reactivation of human herpesvirus 6 in patients with autoimmune connective tissue diseases[J].{H}Journal of Medical Virology,2013,(11):1925-1934.
  • 5Hata TR,Afshar M,Miller J. Etanercept decreases the innate immune wounding response in psoriasis[J].{H}EXPERIMENTAL DERMATOLOGY,2013,(09):599-601.
  • 6Tan X,Balkrishnan R,Feldman SR. Infections associated with the use of tumor necrosis factor-α inhibitors in psoriasis[J/OL].J Drugs Dermatol,2013,(3):e41-e45.
  • 7Kim NN,Lio PA,Morgan GA. Double trouble:therapeutic challenges in patients with both juvenile dermatomyositis and psoriasis[J].{H}Archives of Dermatology,2011,(07):831-835.
  • 8Maddin S,Carruthers A,Brown TH. Current dermatologic therapy[M].Philadelphia:Saunders Press,1982.123-125.
  • 9Blank M,Asherson RA,Cervera R. Antiphospholip in syndrome in factious origin[J].{H}Journal of Clinical Immunology,2004,(01):212-231.
  • 10Ben CE,Wiener WY,Fadeela A. Antiphospholipid antibodies during infectious mononucleosis and their long term clinical significance[J].{H}Journal of Clinical Virology,2013,(04):312-315.

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部