摘要
目的探讨磁共振弥散加权成像（DWI）在病毒性脑炎诊断中的价值。方法对20例诊断病毒性脑炎患儿行常规磁共振成像（T2WI-T1WI）和DWI检查，比较3种成像的异常率和发现的病变部位。结果DWI异常率明显高于T1WI（χ^2=4．44 P〈0．05）。而DWI和T2WI的异常率无明显差异（χ^2=1．20 P〉0．05）。12例病后1周内同时作T1WI、T2WI和DWI检查。5例T1WI和2例T2WI正常者DWI均显示异常；2例T2WI与DWI发现的病灶部位数相同，8例DWI发现的病灶部位数多于T1WI和T2WI。5例于发病1周后同时作T1WI、T2WI和DWI检查，三者异常率相同，发现的病变部位也基本相同。14例发病10～35d复查MRI，多数未能恢复正常。结论DWI对发现病毒性脑炎急性期的病灶较T1WI或T2WI敏感。DWI在急性病毒性脑炎的诊断中具有重要价值。
Objective To explore the application of diffusion weighted imaging （DWI） in diagnosis of viral encephalitis in children. Methods Conventional MR imaging （T2WI and T1WI） and DWI were performed on 20 patients with viral encephalitis diagnosed clinically. Location and number of lesions demonstrated on these imagings and percents in their abnormality were compared. Results Percentage of abnormality demonstrated on DWI was significantly higher than that on T1WI （χ^2 = 4.44 P 〈 0.05）, and there was no significant difference in abnormal percentage between DWI and T2WI. T1WI, T2WI and DWI were simultaneously performed on 12 patients within one week after onset. DWI demonstrated the lesions that were not seen on T1WI in 5 patients and on T2WI in 2 patients. T2WI and DWI in 2 patients demonstrated the same lesions. In 8 patients, DWI detected more lesions than T1WI and T2WI. T1WI, T2WI and DWI were simultaneously performed at 5 patients after one week of onset. These imagings demonstrated similar lesions and percent in abnormality demonstrated by these imagings were same. MR imagings were subsequently performed in 14 patients 10 - 35 days after onset, and most of the lesions had not recovered. Conclusions DWI is more sensitive than T1WI and T2WI in detecting the lesions at the acute stage of viral encephalitis. DWI is of important value in diagnosis of acute viral encephalitis.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2006年第22期1570-1571,共2页
Journal of Applied Clinical Pediatrics
关键词
磁共振
弥散加权成像
脑炎
病毒性
诊断
magnetic resonance imaging
diffuse weighted imaging
encephalitis, viral
diagnosis
