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拓扑替康联合顺铂治疗晚期非小细胞肺癌32例

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摘要 目的评价拓扑替康(TPT)与顺铂(DDP)联合治疗晚期非小细胞肺癌(NSCLC)的疗效及毒副反应。方法TPT1mg/m2,静脉滴注,第1 ̄5天;DDP25mg/m2,静脉滴注,第1 ̄4天;每21 ̄28d重复为1周期,连用2个周期后评价疗效。结果本组32例中完全缓解(CR)1例,部分缓解(PR)14例,总有效(CR+PR)率46.9%。主要毒副反应是骨髓抑制和胃肠道反应。结论TPT联合DDP治疗晚期NSCLC是一个安全、有效、经济的化疗方案,值得临床进一步推广。
出处 《肿瘤研究与临床》 CAS 2006年第11期765-766,共2页 Cancer Research and Clinic
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