摘要
目的:分析9种药物血药浓度监测结果,为临床合理用药提供参考。方法:分别采用 FPIA 法、ELISA 法和 UV 法测定9种药物的血药浓度,对7757例患者31423例次血药浓度监测结果进行比较分析。结果:9种药物31423例次血药浓度监测结果在治疗窗浓度范围内的25221例次,占总数的80.3%,小于治疗窗浓度范围的3033例次,占总数的9.6%,大于治疗窗浓度范围的3169例次,占总数的10.1%。结论:治疗药物监测能为临床合理用药提供客观的依据。
Objective： To analyze the monitoring results of blood concentrations from 9 drugs in this hospital. Method： The blood concentrations of 9 drugs were measured by fluorescence polarization immunoassay, ELISA and UV, respectively. The blood concentrations of 9 drugs in 31 423 samples from 7 757 patients were compared and analyzed. Result： Among 31423 samples, the blood concentrations of 9 drugs in the therapeutic window were 80.3%, The rate of serum concentrations which were lower and higher than the thrapeutic window were 9.6% and 10.1% ,respectivly. Conclusion： Therapeutic drug montoring can offer the external basis for reasonable usage of the drug in clinic.
出处
《中国药师》
CAS
2006年第12期1136-1137,共2页
China Pharmacist
