摘要
目的探讨生大黄联合生长抑素八肽对重症急性胰腺炎的治疗价值。方法将68例重症急性胰腺炎患者随机分为二组:A组34例,为生长抑素八肽联合生大黄治疗组;B组34例,为生长抑素八肽(奥曲肽)治疗组。观察患者治疗前和治疗后第10d的APACHEⅡ评分及治疗后腹痛缓解时间,首次排便时间、并发症发生率及平均住院天数。结果二组治疗失败率无显著差异(P>0.05)。A组腹痛缓解时间、通便时间及平均住院天数短于B组,差异有显著性(P<0.01)。结论联合应用生长抑素八肽和生大黄治疗重症急性胰腺炎有协同作用,疗效优于单一的西药或中药治疗。
Objective To study the therapeutic effect of combining rhubarb and octreotide in treating sever acute pancreatitis （SAP）. Methods 68 patients were randomly divided into two groups ： group A, treated with octreotide and rhubarb, n = 34 ; group B, treated by octreotide, n = 34. APACHEⅡ score, clinical symptoms, the incidence of complication and average hospitalization days were observed and recorded. Chi square test and t test were used in statistical analysis. Results There was no significant difference （ P 〉 0.05 ） in the rate of therapeutic failure among two groups. The times of first stool, abdominal pain relief and average hospitalization day were significantly shorter in group A than that in group B （ P 〈 0.01 ） , respectively. APACHE Ⅱ score of 10 days after treatment was significantly lower in group A. Conclusion The therapeutic effect of combining octreotide with rhubarb in treatment of severe acute pancreatitis is superior to only use octreotide.
出处
《医药论坛杂志》
2006年第21期32-33,共2页
Journal of Medical Forum
