摘要
通过饮水加氟、加硒的方法，观察氟、硒对大鼠精子形态学指标的影响。结果表明，氟可使大鼠精子数目减少，精子活动率和活动度降低，精子畸形率升高，给氟同时给予硒，则可以拮抗氟的这种作用。说明氟对大鼠存在生殖毒性，而加硒则可以拮抗氟的生殖毒性。
Sodium fluoride and sodium selenite in deionized water were administered to male rats for 8 weeks. The count, mobility and morphological change of sperm were observed. The present results showed that NaF could reduce the sperm count and sperm mobility, and increase the abnormal sperm significantly. It was found that combined administration of fluoride and selenium to male rats could decrease this kind of effect of fluoride. Thus, it could be concluded that fluoride can cause the reproductive toxicity in male rats, indeed, whereas selenium can antagonize with the reproductive toxicity of fluoride.
出处
《中国地方病学杂志》
CAS
CSCD
1996年第4期202-204,共3页
Chinese Jouranl of Endemiology
基金
国家教委资助
关键词
氟
硒
毒性
生殖毒性
大鼠
Fluoride Selenium Reprodective toxicity Male rats
