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高龄ST段抬高急性心肌梗死患者早期介入治疗对左心室重构的影响 被引量:3

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摘要 目的评价高龄ST段抬高急性心肌梗死(STEMI)患者早期介入干预对心肌纤维化及左心室重构的影响。方法将因STEMI入院治疗、年龄≥70岁的86例患者根据是否行早期冠状动脉介入(PCI)治疗分为PCI组和保守治疗组;随访6个月,观察就诊时及STEMI后第7天、3个月、6个月血液氮末端脑钠肽前体(NT-proBNP)、透明质酸酶(LN)、Ⅲ型前胶原氨基端肽(PⅢNP)水平并行超声心动图检查,随访心血管事件发生情况。结果随访结束PCI组和保守治疗组心血管事件发生率分别为11.9%和18.8%(P>0.05);心肌梗死患者发病时NT-proBNP、PⅢNP、LN水平较心绞痛组明显增高(P<0.05);左心室收缩末期容积(LVESV)增高,左心室射血分数(LVEF)减低(P<0.05)。PCI组NT-proBNP水平于STEMI后3个月和6个月较保守治疗组明显减低(P<0.05);PⅢNP和LN水平在STEMI后6个月明显减低(P<0.05);左心室舒张末期容积(LVEDV)在STEMI后6个月较保守治疗组明显减小(P<0.05),而LVEF明显增高(P<0.05)。6个月时PCI组室壁运动指数明显小于保守治疗组(P<0.05)。结论高龄STEMI患者早期介入干预可减缓心室重构,改善预后。
出处 《中国综合临床》 北大核心 2006年第12期1064-1067,共4页 Clinical Medicine of China
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参考文献6

  • 1袁祥光,杨云,王智明,陈玉兰.急性心肌梗死优化介入治疗的临床研究[J].中国基层医药,2006,13(2):241-242. 被引量:6
  • 2高润霖.急性心肌梗死诊断和治疗指南[J].中华心血管病杂志,2001,29(12):710-725. 被引量:4974
  • 3Mair J,Lercher AH,Puschendort B.The impact of cardiac natriuretic peptide determination on the diagnosis and management of heart failure[J].Clin Chem Lab Med,2001,39(7):571-588.
  • 4Uusimaa P,Risteli J,Niemela M..Collagen scar formation after acute myocardial infarction:relationships to infarct size,left ventricular function,and coronary artery patency[J].Circulation,1997,96(8):2 565-2 572.
  • 5Nagaya N,Goto Y,Nishikimi T,.Sustained elevation of plasma brain natriuretic peptide levels associated with progressive ventricular remodeling after acute myocardial infraction[J].Clin Sci,1999,96(2):129-136.
  • 6Visser CA.Infarct-related artery patency and long-term effects on left ventricular remodeling[J].Cardiology,1997,88 (Suppl):26-35

二级参考文献5

  • 1梁转合,朱可云,陈华发,陶卫国,陈影霞,黄惠玲.急性心肌梗死施行急诊冠脉介入治疗与常规治疗的对照研究[J].中国基层医药,2005,12(3):286-288. 被引量:7
  • 2Birnbaum Y, Goodman S, Barr A, et al. Comparison of primary coronary angioplasty versus thrombolysis in patients with ST-segment elevation acute myocardial infaretion and grade Ⅱ and grade Ⅲ myocardial ischemia on the enrollment electrocardiogram. Am J Cardiol,2001,88(8) :842-847.
  • 3Ellis SG, Da-Silva ER, Spaulding CM, et al. Review of immdiate angioplasty after fibrinolytic therapy for acute myocardial infaretion: insights from the RESCUE Ⅰ . RESCUE Ⅱ , and other contemporary clinical experiences. Am Heart J, 2000,139(6) : 1046-1053.
  • 4Grech ED, Sutton AG, Campbell PG, et al. Reappraising the rle of immediate imervention following, thrombolytic recanalization acute myocardial in farct ion. AM J Cardiol, 2000,86 (4) : 400-450.
  • 5高润霖.急性心肌梗死诊断和治疗指南[J].中华心血管病杂志,2001,29(12):710-725. 被引量:4974

共引文献4976

同被引文献18

  • 1黄鹏,张福春,郭丽君,李海燕,牛杰,陈风荣,毛节明,郭静萱,赵一鸣,高炜.介入治疗对ST段抬高的急性心肌梗死患者1~5年病死率的影响[J].中国综合临床,2006,22(4):295-298. 被引量:3
  • 2杨跃进,毛懿,倪新海,陈纪林,高润霖,陈在嘉.B型尿钠肽水平对急性心肌梗死患者心源性死亡的预测价值[J].中华内科杂志,2007,46(6):450-453. 被引量:23
  • 3MICHAEL W,CHRISTIAN H.Role of B-type natriuretic peptide (BNP) and NT-proBNP in clinical routine[J].Heart,2006,92:843-849.
  • 4DELEMOS J,MORROW D,BENTLEY J,et al.The prognostic value of B-type natruretic peptide in patients with acute coronary syndrome[J].N Engl J Med,2001,345:1014-1021.
  • 5TERUO I,MASASHI S,ISAO Y,et al.Early recanalization and plasma brain natriuretic peptide as an indicator of left ventricular function after acute myocardial infarction[J].Am Heart J,2002,143:790-796.
  • 6GUNES Y,OKCUN B,KAVLAK E,et al.Value of brain natriuretic peptide after acute myocardial infarction[J].Anadolu Kardiyol Derg,2008,8:182-187.
  • 7MORROW M D,DE LEMOS M D,BLAZING M D,et al.Prognostic value of serial B-type natriuretic peptide testing during follow-up of patients with unstable coronary artery disease[J].JAMA,2005,294:2867-2871.
  • 8Michael W,Christian H.Role of B-type natriuretic peptide (BNP)and NT-proBNP in clinical routine.Heart,2006,92:843-849.
  • 9Martinez-Rumayor A,Richards AM,Burnett JC,et al.Biology of the natriuretic peptides.Am J Cardiol,2008,101:3A-8A.
  • 10Gunes Y,Okcun B,Kavlak E,et al.Value of brain natriuretic peptide after acute myocardial infarction.Anadolu Kardiyoloji Dergisi,2008,8:182-187.

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