摘要
目的:建立测定人尿样中碘离子浓度的离子色谱法。方法:采用离子色谱,在IonPacAS7柱上,用50mmol/L的硝酸为淋洗液测定尿液中碘离子的含量。检测方式为直流安培检测,工作电极为Ag电极,参比电极为Ag/Agcl电极。结果:碘离子浓度检测线性范围为50～1000μg/L(r=0.9998),平均回收率为95.8%～97.0%,相对标准偏差为2.6%～3.7%;测得的正常人尿碘浓度为100～300μg/L。结论:该方法稳定、准确、快速,可用于实际样品的测定。
OBJECTIVE： To establish ion chromatography for the determination of iodine ion concentration in human urine .METHODS： Iodine ion concentration was determined using chromatography of ions,the determination was performed on Poe ＊AS7 column with 50mmol/L nitric acid as the elutriant.The detection was by means of DC amperometer detector with Ag as working electrode and Ag/AgCl as reference electrode.RESULTS： The linear range of iodine ion concentration was 50- 1 000μg/L（ r = 0.9 998）, the average recoveries were 95.8 % -97.0 % with RSD at 2.6 % -3.7 %. The iodine ion concentration in health adults was detected at 100-300μg/L.CONCLUSION： The established method is stable, accurate and fast, and suitable for the determinate of iodide in human urine.
出处
《中国药房》
CAS
CSCD
北大核心
2006年第23期1794-1796,共3页
China Pharmacy
关键词
离子色谱
尿碘
浓度
Ion chromatography
Urine iodine
Concentration
