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乳腺癌多药耐药基因的表达及意义 被引量:1

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摘要 用组织芯片技术和免疫组化法检测28例乳腺癌标本中多药耐药基因G STπ-、P-gp、T op-Ⅱ的表达情况。结果显示,乳腺癌G ST-π基因表达阳性率64.2%,P-gp 25%,T op-Ⅱ57.1%,多药耐药基因阳性表达与患者年龄、淋巴结转移、雌激素受体及孕激素受体无关。提示G ST-π、P-gp、T op-Ⅱ表达可作为乳腺癌患者化疗耐药的评价指标。
作者 周新颖
机构地区 迁安市人民医院
出处 《山东医药》 CAS 北大核心 2006年第34期67-68,共2页 Shandong Medical Journal
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