1Strich S J. Sheari ng of nervefibres as a cause of brain damage due to head injury. Lancet, 1961,2 :433
2Adams J H, Doyle D, Ford I, et al. Diffuse axonal injury in head injury,definition, diagnosis and grading. Histopathol, 1989,15:49~59
3Gennarelli T A, Thibault L E, Adams J H, et al. Diffuse axo nal injury andtraumatic coma in the primate. Ann Neurol, 1982,12(6):564~574
4Nishimoto T, Murakami S. Relation between diffuse axonal in jury and internal headstructures on blunt impact. J Biomech Eng, 1998,120(1): 140~147
5Graham D I, Clark J C, Adams J H, et al. Diffuse axonal inj ury caused by assault.J Clin Pathol, 1992,45:840~841
6Levi L, Guiburd J N, Lemberger A, et al. Diffuse axonal inj ury: Analysis of 100patients with radiological signs. Neurosurgery, 1990,27(3): 429~432
7Parizel P M, McGowan J C, Grossman R I, et al. Imaging find ing in diffuse axonalinjury after closed head trauma. Eur Radiol, 1998,8(6):9 60~965
8Christman C W, Grady M S, Walker S A, et al. Ultrastructur al studies of diffuseaxonal injury in humans. J Neurotrauma, 1994,11(2):173~1 86
9Yamaki T, Murakami N, Iwamoto Y, et al. Pathological study of diffuse axonal injurypatients who died shortly after impact. Acta Neurochir (Wien), 1992,119:1~4,153~158
10Grady M S, McLaughlin M R, Christman C W, et al. The use of antibodies targetedagainst the neurofilament subunits for the de tection of diffuse axonal injury in humans.J Neuropathol Exp Neurol, 1993,52(2) :143~152
2Smith DH,Chen XH,Iwata A,et al.Amyloid beta accumulation in axons after traumatic brain injury in humans[J]. J Neurosurg,2003,98(5):1072-1077.
3Tarr PE,Contursi C,Roncarati R,et al.Evidence for a role of the nerve growth factor receptor TrKA in tyrosine phosphorylation and processing of beta APP[J]. Biochem Biophys Res Commun,2002,295(2):324-329.
4Hall ED,Oostveen JA,Dunn E,et al.Increased amyloid protein pre-cur-sor and apolipoprotein E immunoreactivity in selectively vulner-able hip-pocampus following transient forebrain ischemia in gerbils[J]. Exp Neu-rol,1995,135(1):17-27.
5Wallace WC,Aakar CA,Lyons WE.Amyloid precursor protein po-tenti-ates the neurotrophic activity of NGF[J]. Brain Res Mol Brain Res,1997,(52):201-212.
6Kienlen-Campard PK,Tasiaux B,Octave JN.The processing and bi-olog-ical function of the human amyloid precursor protein:lessons from dif-ferent cellular models[J]. Exp Geronto,2000,35:843-850.
7Nakagawa T,Zhu H,Morishima N,et al.Caspase-12mediates endo-plas-mic-reticulum-specific apoptosis and cytotoxicity by amy-loid-beta[J]. Nature,2000,403(6765):98-103.
8Bryan-sisneros AA,Fraser SP,Sun YH,et al.Toxic effect of the be-ta-amyloid precursor protein c-terminus fragment and Na+.Ca+gradi-ents[J]. Neuroreport,2000,11(15):3357-3360.