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丙型肝炎抗病毒治疗研究进展 被引量:50

Advances in research of antiviral agents for hepatitis C
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摘要 丙型肝炎由于进展隐匿、慢性率高及预后不良而倍受关注。研究发现,约20%慢性丙型肝炎患者将进展为肝硬化,约2.5%最终罹患肝癌。据估计,全球有1.7亿丙型肝炎病毒(HCV)携带者,我国人群HCV感染率约在3%左右。以干扰素为基础的治疗在临床上一直居于主导地位,特别是聚乙二醇化干扰素(Peg—IFN)联合利巴韦林的应用使病毒学应答率明显提高。但是,疗程长、有效率低、不良反应大等问题仍未得到根本解决。
作者 康富标 赵敏
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2006年第12期933-935,共3页 Chinese Journal of Hepatology
关键词 肝炎 丙型 抗病毒药物 Hepatitis C Antiviral agents
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