摘要
目的:观察酸枣仁汤的镇静催眠作用。方法:将100只小鼠随机分为酸枣仁汤大、中、小剂量组、安定组、生理盐水组共5组,各组分别灌胃给予相对应药物,再将每组小鼠分为A组和B组(B组注射戊巴比妥钠)。观察各组药物对所有A组小鼠自主活动次数的影响及对B组小鼠睡眠时间的影响和各组小鼠的大脑重量。结果:大剂量的酸枣仁汤能减少A组小鼠自主活动次数,但与生理盐水组相比,差异并不显著。中剂量的酸枣仁汤能显著延长B组小鼠的睡眠时间,增加所有小鼠大脑重量。结论:酸枣仁汤在不同剂量时发挥不同的药效。
Objective：To observe the sedative and hypnotic effects of Suanzaoren decoction. Methods：100 mice were randomized into saline group, antipsychotic group, Suanzaoren decoction group 1 （low dosage）, group 2 （medium dosage）, group 3（high dosage）. Every group was randomized into group A and group B（injected pentobarbital sodium）. The spontaneous motion of group A,sleeping time of group B were observed and cerebral weight of all mice were weighed. Results： High dosage Suanzaoren decoction could inhibit spontaneous motion, but there is no significant difference compared with saline group. Medium dosage Suanzaoren decoction could prolong the sleeping time of mice injected pentobarbital sodium and increase cerebral weights of mice. Conclusions：Suanzaoren Decoction have different effects in different dose.
出处
《山西中医学院学报》
2006年第6期19-20,共2页
Journal of Shanxi College of Traditional Chinese Medicine
关键词
酸枣仁汤
镇静
催眠
Suanzaoren decoction
sedation
hypnosis
