摘要
目的:口腔非特异性(NOS)溃疡是一类与HIV感染有关的口腔病变,其临床表现不同于常见口腔溃疡。通过对NOS口腔溃疡临床特征的分析,为临床医师提供鉴别诊断。方法:回顾性分析72例HIV/AIDS患者,NOS口腔溃疡有3例,探讨其临床特征并与复发性阿弗他溃疡、单纯疱疹性口炎进行比较,探讨其发病机制。结果:NOS口腔溃疡的好发部位为软腭、口咽及舌腭弓处,常为1~2个,病程较长,cD。+细胞明显减少,多伴发白色念珠菌感染。结论:NOS口腔溃疡的发病部位、病程与预后较为特殊,与AIDS的病程进展有一定的联系。
Objective: Ulceration NOS (not otherwise specified ) was a sort of oral lesions associated with HIV infection which had special clinical manifestations. The features of ulceration NOS were described and the differential diagnosis were provided for the clinican. Methods: A toatal of 72 HIV - infected/AIDS individuals were examined for oral ulcers. Ulceration NOS was found in 3 patients, of which the clinical manifestations were described and compared with recurrent aphthous ulcers and herpetic stomatitis. The pathogenesis of ulceration NOS was discussed. Results: Ulceration NOS lesions with a predilection for the soft palate, the oropharynx and the anterior palatine were observed. The clinical features were ulceration number (one or two), duration( more than 3 months), and CD4+ T cell count (reduced obviously). Two of three patients had concomitant candida albicans infection. Conclusion: Ulceration NOS was a special sort of ulceration in the sites, the course of disease and the prognosis, which had some connection with the course of AIDS.
出处
《口腔医学研究》
CAS
CSCD
2006年第6期629-631,共3页
Journal of Oral Science Research
基金
湖北省自然科学基金资助项目(编号:2004ABA168)
关键词
艾滋病
HIV
口腔非特异性(NOS)溃疡
Ulceration NOS (not otherwise specified)
HIV
Acquired immune deficiency syndrome(AIDS)