摘要
目的探讨经导管消融治疗并发于原发性甲状腺机能亢进（简称甲亢）的心房颤动（简称房颤）的效果。方法18例甲亢并发房颤患者，均经抗甲亢治疗控制甲状腺激素水平在正常范围内3个月以上，仍伴有发作频繁、症状严重，经抗心律失常药物治疗无效的阵发性或持续性房颤。在三维电解剖标测系统和肺静脉环状标测联合指导下行环绕两侧肺静脉的线性消融。消融终点为双侧肺静脉的电学隔离。结果18例患者术中均达到消融终点。随访12．6±6．8（4-27）个月，13例（72％）患者在不服用任何抗心律失常药物前提下无房颤发作，5例（28％）房颤复发。无任何操作相关并发症。结论对于发生于甲亢患者的房颤，三维标测系统指导下的环肺静脉线性消融术是一项可供选择的治疗措施。
Objective To evaluate the outcome of patients with hyperthyroidism and atrial fibrillation （AF） treated with trans-catheter ablation. Methods 18 highly symptomatic patients with hyperthyroidism and antiarrhythmic drugs （AADs） refractory AF had been rendered euthyroid for more than 3 months. Ablation was guided by 3-D electroanatomie mapping combined with circumferential pulmonary vein （PV） mapping. The endpoints of the ablation were defined as the PV isolation. Results The procedure endpoints were achieved in all patients. During 12.6 ± 6.8 months follow-up, 13 patients were free of atrial tachyarrhythmias without any AADs. AF relapsed in 5 patients. No procedure-related complications were observed. Conclusion Complete isolation of PVs using circumferential ablation approach guided by 3-D electroanatomic mapping may be a potentially choice for the treatment of AADs resistant and symptomatic AF in patients with post-hyperthyroidism.
出处
《中国心脏起搏与心电生理杂志》
2006年第6期494-496,共3页
Chinese Journal of Cardiac Pacing and Electrophysiology
基金
国家十五攻关课题资助项目(2004BA714B04)
关键词
心血管病学
甲状腺机能亢进
心房颤动
肺静脉
射频消融
导管电流
Cardiology
Hyperthyroidism
Atrial fibrillation
Pulmonary vein
Catheter ablation, radiofrequency current
