摘要
【目的】评价动脉导管未闭（PDA）应用国产蘑菇伞封堵治疗后及中期随访的左室功能变化。【方法】对45例PDA患者封堵术前、术后及3～6个月随访时行经胸超声检查（TTE），测量左室舒张末期内径（LVE叻）、左室舒张末期容积（LVEDV）、左室收缩末期容积（LVESV）、左室每搏量（LVSV）、左室射血分数（LVEF）和左室短轴缩短率（LVFS）。【结果】封堵术后LVEDD、LVEDV、LVESV与LVSV减少，3～6个月随访时进一步下降；LVEF与LVFS封堵术后较封堵术前下降，3～6个月随访时未见进一步改变。【结论】国产蘑菇伞封堵治疗PDA，减轻左室容量负荷，封堵术后早期代偿增强的左室功能回复，中期随访左室功能维持在正常水平。
[Objectlve]To evaluate the early and mid-term changes of left ventricular function after transcatheter closure of patent ductus arteriosus（PDA） with the domestic mushroom occluder. [Methods]Fortyfive patients with PDA underwent transthoracic echocardiographic examination （TTE） before and after closure and during a mid-term follow-up respectively. The left ventricular end-diastolic diameter （LVEDD）, left ventricular end-diastolic volume （LVEDV）, left ventricular end-systolic volume （LVESV）, left ventricular stroke volume （LVSV）, left ventricular ejection fraction （LVEF） and left ventricular fractional shortening （LVFS） were measured. [Results]The LVEDD, LVEDV, LVESV and LVSV were significantly reduced after closure and continuously reduced during 3-6-month follow-up. The LVEF and LVFS were lower after closure than before, while no evident difference was found between early TTE examination after closure and during 3-6- month follow-up. [Conclusion]Transcathter closure of PDA with the domestic mushroom occluder can decrease the left ventricular preload. In the early term after closure, compensative enhanced left ventricular function gradually returns to nearly normal level. During the mid-term follow-up, left ventricular function is stable on normal level.
出处
《医学临床研究》
CAS
2006年第12期1951-1953,共3页
Journal of Clinical Research
关键词
动脉导管未闭
心室功能
左
ductus arteriosus,patent
ventricular function,left
