摘要
脂肪组织被认为不仅是能量储存器官,而且是功能活跃的内分泌器官。脂肪因子在代谢综合征的发生、发展过程中起重要作用,尤其是肥胖时内脏脂肪组织分泌的促炎症脂肪因子可直接导致胰岛素抵抗和血管损伤,充分理解脂肪组织的内分泌功能将有助于对代谢综合征作出更合理的治疗。
Adipose tissue is not simply a depot of energy, but is an active endocrine organ. The adipo- kines play an important role in the pathogenesis of metabolic syndrome. The proinflammatory adipokines secreted from expanded visceral adipose tissue directly induce insulin resistance and vascular injuries. A better understanding of the endocrine function of adipose tissue may lead to more rational therapy for metabolic syndrome.
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
2006年第6期840-844,共5页
Acta Academiae Medicinae Sinicae
基金
上海市教育委员会科研资助项目(05BZ28)~~
