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连接蛋白与遗传性耳聋 被引量：2

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摘要 编码缝隙连接蛋白的Connexcin(Cx)基因突变是非综合征型耳聋的分子遗传基础。本文从它们在组织和器官的表达、突变类型、引起耳聋的机制等方面的研究进展进行综述。探讨其可能的发病机制为基因诊断,预防及治疗提供了新的理论依据。
作者 郝津生 张亚梅 戴朴 张杰
机构地区 首都医科大学附属北京儿童医院耳鼻咽喉科 中国人民解放军总医院耳鼻咽喉头颈外科
出处 《国际耳鼻咽喉头颈外科杂志》 2006年第6期371-375,共5页 International Journal of Otolaryngology-Head and Neck Surgery
关键词 连接蛋白类(Connexins) 遗传性疾病 先天性(Genetic Diseases Inborn) 聋(Deafness)
分类号 R764.43 [医药卫生—耳鼻咽喉科]
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参考文献29

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二级参考文献14

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国际耳鼻咽喉头颈外科杂志
2006年 第6期

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