摘要
目的研究白术挥发油对动物移植性肿瘤的作用。方法以动物移植性肿瘤艾氏腹水癌(ECA)等为模型,观察白术挥发油的抗肿瘤作用。结果白术挥发油以100mg/kg及50mg/kg剂量腹腔给药时,对ECA均有较强的抑制作用;且大剂量给药1次(150mg/kg),可延长患瘤小鼠的寿命197%。结论白术挥发油具有抑制肿瘤的作用。
Objective To study the function of atractylodes macrocephala koidz volatile oil for transplanted tumor in animals. Methods The animal model of transplanted tumor-ECA was used. The antl-tumor function of atractylodes maerocephala koidz volatile oil was observed. Results Atractylodes macrocephala koidz volatile oil can suppress ECA when given at 100 mg/kg and 50 mg/kg doses into abdominal cavity. When a larger dose at 150 mg/kg was given, the life-span of mice can extended to 197 %. Conclusion Atraetylodes macrocephala koidz volatile oil can suppress tumor effectively.
出处
《肿瘤研究与临床》
CAS
2006年第12期799-800,共2页
Cancer Research and Clinic
基金
山西省自然科学基金资助项目(20001079)
关键词
白术挥发油
移植性肿瘤
Atractylodes macrocephala koidz volatile oil
Transplanted tumor
