摘要
目的:调查沈阳地区不同人群乙型肝炎病毒(HBV)的感染情况。方法:对6 974例在我院住院的病人分为14岁以下、15岁以上和孕妇3组,用ELISA法进行HBV血清学标志物检测,比较各组间HBV的感染情况。结果:14岁以下组HBsAg阳性率明显低于15岁以上组(P<0.05),乙肝表面抗体(抗-HBS)的阳性率高于15岁以上组,孕妇HBV感染率与普通人群无显著性差异。结论:沈阳地区儿童HBsAg阳性率下降的主要原因可能与乙肝疫苗的广泛接种有关。
Objective： To investigate hepatitis B virus （HBV） infection in different populations of Shenyang city. Methods ：A total of 6974 patients admitted to the hospital were divided into 3 group： group 1 （ patients aged 14 years and younger）, group 2 （ patients aged 15 years and older）, and group 3 （pregnant women）. HBV serum markers were detected by using enzyme linked immunosorbent assay （ELISA） and compared among 3 groups. Results：The positive rate of HBsAg in group 1 was significantly lower than that in group 2, and the positive rate of anti-HBs in group 1 was significantly higher than that in group 2. No significant difference in HBV infection rate was found between group 2 and group 3. Conclusion ：The decrease in the positive rate of HBsAg in children may be the resuit of universal HBV vaccination.
出处
《中国医科大学学报》
CAS
CSCD
北大核心
2006年第2期181-182,共2页
Journal of China Medical University
基金
辽宁省自然科学基金资助项目(9919599706)
关键词
乙型肝炎病毒
感染
流行
hepatitis B virus
infection
prevalence
