期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

肺癌患者血清CEA和CA125检测的临床应用 被引量：1

下载PDF
导出
摘要 目的探讨CEA和CA125检测对肺癌鉴别诊断和疗效观察的临床意义。方法采用免疫放射分析法测定40例健康人和按组织学分类的87例各类肺癌患者血清CA125、CEA水平及阳性率,进行统计分析。结果肺癌患者CA125、CEA水平较健康对照组高(P<0.01),经综合治疗后均有下降;不同类型肺癌的CEA和CA125阳性率差异无显著性(P>0.05),但其中肺鳞癌CA125阳性率(为84%)相对较高。结论血清CEA和CA125可作为肺癌早期诊断、鉴别诊断及观察疗效的较好参考指标。
作者 沈加玲
机构地区 江苏省金湖县人民医院
出处 《现代实用医学》 2006年第12期886-887,共2页 Modern Practical Medicine
关键词 糖类抗原CA125 肺肿瘤 癌症 癌胚抗原 免疫放射分析法
分类号 R734.2 [医药卫生—肿瘤]
  • 相关文献

参考文献3

二级参考文献20

  • 1Shimizu A, Shiraki K, lto T, et al. Sequential fluctuation parrern of serum des-gamma-carboxy prothrombin levels detected by high-sensitive electrochemiluminescence system as an early predictive marker for hepatocellular carcinoma in patients with cirrhos
  • 2Nomura F, Ishijima M, Kuwa K, et al. Serum des-gamma-carboxy prothrombin levels determination by a new generation of sensitive immunoassays in patients with small-sized hepatocellular carcinom[J]. Am J Gastroenterol, 1999, 94(3): 650-654.
  • 3Wesseling S, Stephan C, Semjonow A, et al. Determination of non-alpha-antichymotrypsin-complexed prostate-specific antigen as an indirect measurement of free prostate-specific antigen: analytical performance and diagnostic accuracy[J]. Clin Chem, 2003, 49
  • 4Sanchez C, Espasa A, Chinchilla V, et al. New electrochemilumi nescent immunoassay for the determination of CYFRA21-1: analytical evaluation and clinical diagnostic performance in urine sam ples of patients with bladder cancer[J]. Clin Chem, 1999, 45(11):
  • 5Yan G, Ju H, Liang Z, et al. Technical and clinical comparison of two fully automated methods for the immunoassay of CA125 in serum [J]. J Immunol Methods, 1999, 225(1-2): 1-8.
  • 6Deng YF, Chen P, Lin YZ, et al. Analytical and clinical evaluation of CYFRA21-1 by electrochemiluminescent immunoassay in head and neck squamous cell carcinoma[J]. J Laryngol Otol, 2003, 117 (3): 190-194.
  • 7Shimada M, Yamashita Y, Hamatsu T, et al. The role of desgamma-carboxy prothrombin levels in hepatocellular carcinom and liver tissues[J]. Cancer Lett, 2000, 159(1): 87-94.
  • 8Geiger DU, Wu AHB, Apple FS, et al. Multicenter evaluation ofan automated assay for troponin I[J]. Clin Chem, 2002, 48(6Pt1): 869-876.
  • 9Candido DRFJ, Moreirade AJ, Bighetti S. CA125 and vascular endothelial growth factor in the differential diagnosis of epithelial ovarian tumors [J]. Gynecol Obstet Invest, 2002, 54(3): 132-136.
  • 10Fujiwara H, Kinugasa H, Inaoka Y. Basic and clinical evaluation of the automatic chemiluminescent immunoassay apparatus ARCHITECT CA199[J]. Igaku Yakugaku, 1999, 41(5): 1031-1041.

共引文献46

同被引文献6

  • 1Siegel R,Ward E,Brawley O,et al. Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths[J]. CA Cancer J Clin, 2011,61 (4) : 212-236.
  • 2Jang SM,Kim JW,Kim CH,et al. p19 (ras) Represses proliferation of non-small cell lung cancer possibly through interaction with Neuron- Specific Enolase (NSE)[J]. Cancer Letters, 2010,289 ( 1 ) : 91-98.
  • 3Ando S,Suzuki M ,Yamamuto N ,et al. The prognostic value of bnth neu- ron-specific enolase (NSE) and Cyfra21-1 in small cell lung cancetiJ1. A n- ticancer Research, 2004,24 (3B) : 1941 - 1946.
  • 4Schneider J,Philipp M,Velcovsky H(;,et al. Pro-gastrin-releasing pep- title (ProGRP), neuron specific enolase (NSE), carcinoembryonic antigen (CEA) anti cytokeratin 19-fragments (CYFRA 21-1) in patients with lung cancer in comparison to other lung disease[J]. A nticancer Research ,2003,23 (2A) : 885-893.
  • 5陈建忠,顾利江.肺癌患者血清CEA、NSE、CA19-9和VEGF检测的临床意义[J].中国现代医生,2011,49(8):28-29. 被引量：8
  • 6张勇华.联合检测多种肿瘤标志物对肺癌诊断的临床价值[J].中国现代医生,2012,50(2):66-67. 被引量：8

引证文献1

二级引证文献2

现代实用医学
2006年 第12期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部