摘要
报道高温环境对腹腔巨噬细胞表面Ｃ３ｂ受体的影响．将９１只ＳＤ大鼠随机分为七组：①受热１ｈ（４０．０±０．５℃）组，②单纯游泳组（３０．０—３２．０℃），③受热１ｈ（４０．０±０．５℃）延期４ｈ）（室温）活杀组，④受热１ｈ（４０．０±０．５℃）延期２４ｈ（室温）活杀组，⑤受热２ｈ（４０．０±０．５℃）组，⑥受热１ｈ（４０．０±０．５℃）加游泳（３０．０～３２．０℃）组，⑦对照组（室温）。处死各组大鼠，以绵羊红细胞作花环试验检测腹腔巨噬细胞表面Ｃ３ｂ受体。结果显示：①、②、③、④组花环率分别为１１．９８±４．４０，１１．３０±３．１３，１２．１４±４．２６及１１．７５±３．３０，与⑦组（１１．３８±３．２２）比较无明显差异（Ｐ＞０．０５）；⑤、⑥组花环率分别为８．３０±３．０５和１４．３１±４．８１，与⑦组比较有显著性差异（Ｐ＜０．０１）。本实验通过模拟高温环境，以了解高温环境对机体巨噬细胞免疫功能的影响程度。
This paper reports the effect of high temperature on C 3b receptors on the surfaces of macrophages in abdominal cavity.91 SD rates were randomly divided into 7 groups:①1-hour treated group(40.0±0.5℃),②swimming group(30～32℃),③1 hour treated group(40.0±0.5℃)then staying at room temperature for 4 hours,④1 hour treated group(40.0±0.5℃)then staying at room temperature for 24hours,⑤2 hour treated group(40.0±0.5℃),⑥1 hour treated group (40.0±0.5℃)then swimming(30～32℃)and⑦the control group and after treating all the SD rates were killed for C 3b acfivities detection.The results showed that the RBC rosette formation rates for groups①,②.③and ④were 11.98±4.4,11.30±3.13,12.14±4.26 and 11.75±3.3respectively,compared to that of the control there was no significant difference ( P >0.05);and that for groups⑤and⑥being 8.30±3.05 and 14.31±4.81,showing significant difference with that of the control( P <0.01)and RBC rosette formation rate for group 5 is decreased significently while that for group 6 is increased markedly.By this mimic experiment it is evident that environment temperature change has certain degree influencing the immune function of macrophages of rats and hence hygenic instruction to health care for those who are working in high temperature can be suggested for reference.
出处
《四川省卫生管理干部学院学报》
1996年第4期222-223,共2页
Journal of Sichuan Continuing Education College of Medical Sciences
关键词
SD大鼠
高温环境
巨噬细胞
C3B受体
SD rate,high temperature environment,C 3b receptors on the surfaces of macrophages
