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爱普列特治疗老年良性前列腺增生症疗效观察 被引量:3

Clinical efficacy of epristeride in the treatment of eld benign prostatic hyperplasia
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摘要 目的:观察爱普列特治疗老年良性前列腺增生症(BPH)的临床效果及安全性。方法:入选BPH患者43例,口服爱普列特片5 mg,2次/日,共4个月。结果:服药前后国际前列腺症状评分(IPSS)、生活质量评分(QOL)、残余尿量(Ru)、最大尿流率(Qmax)、前列腺体积(PV)、前列腺特异抗原(PSA)的变化差异均有显著性(P<0.05),4个月时有效率为88.37%。结论:爱普列特是一种治疗BPH安全、有效的药物,值得临床推广应用。 objective: To observe the chinical safety and efficacy of epristeride in the treatment of eld benign prostatic hyperplasia (BPH).Methods:Forty-threc patients with BPH were given epristeride tablets 5mg po,twice daily for 4 moths.Results:The differences in international prostate symptom score(PSS),residual urine(RU),maximum flow rate(Qraax),prostate volume(PV),prostate specific antigenfPSA) before and after the treatment were statisticaUy significant (P〈0.05),the effective rate at the termination of the treatment was 88.37% Conclusion:Epristeride is a safety and Effective drug for the treatment of BPH,which should be clinically popularized.
出处 《现代医药卫生》 2007年第2期174-175,共2页 Journal of Modern Medicine & Health
关键词 爱普列特 良性前列腺增生症 药物治疗 老年 Epristeride Benign prostatic hyperplasia, Drug therapy,Eld
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  • 2Audet P Nurcombe H,Lamb Y,Jorkasky D,et al.Effect of multipledoses of epristends, a steroid 5a-reductase inhibitor, on serumdihydrotestosterone in older male subjects[].Clinical Pharmacology and Therapeutics.1993
  • 3Johnsonbaugh RE,Cohen BR,McCormack EM,et al.Effect of fourteendays treatment with epristeride an uncompetitie 5a-reductase inhibitorOn serum and prostatic testosterone and dihydrotestosterone in men withbenign prostatic hyperpiesia[].Journal d Urologie.1993
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  • 5薛兆英,韩文科,金杰,张元芳,丁强,王晓雄,曹立军.爱普列特治疗良性前列腺增生Ⅱ期临床研究[J].中国临床药理学杂志,2000,16(6):432-435. 被引量:25
  • 6张元芳,丁强,冯善章,蔡松良,王翔.新型5α-还原酶抑制剂-爱普列特治疗良性前列腺增生症Ⅱ期临床试验研究[J].中国临床药理学杂志,2000,16(6):436-439. 被引量:16

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