摘要
目的:观察RSV毛细支气管炎发生哮喘的发生率、影响因素及吸入激素治疗的预防效果。方法:对1999年11月至2003年3月期间在我院住院的217例RSV毛细支气管炎患儿进行回顾性分析。结果:217例RSV毛细支气管炎患儿中,22例进展为哮喘,哮喘发生率为10.1%。其中急性期症状控制后继续吸入皮质激素6个月组哮喘发生率为2.9%(2/69),吸入3个月组为6.7%(5/75),急性期症状控制后不作任何干预组为20.5%(15/73)。三组比较差异有非常显著性意义(x2=13.64,P<0.01)。自身过敏体质、接触过敏原、家族遗传性疾病史、父母吸烟的患儿哮喘发生率较无以上因素的患儿高(P<0.05或0.01)。结论:RSV毛细支气管炎易发展为哮喘,应尽量避免高危因素、早期防治。局部吸入糖皮质激素能有效预防RSV毛细支气管炎日后哮喘的发生。
Objective： To study the incidence, related factors and the preventing effect after inhaling glucocorticoid in asthma children with respiratory syncytial virrus bronchiolitis （ RSV ）. Method： We reviewed the 217 datas of the children from Nov. 1999 to Mar.2003 in our hospital. Result：In all 217 cases , 22 cases were with asthma ,the incidence was 10. 1%. Those were inhaled glucocorticoid arfter 6 monthes , 3 monthes and without interference in the acute period were respectively 2.9 % （2/69） ,6.7 % （5/75） ,20. 5 % （ 15/73 ） o There＇s significant difference among three groups, （ x^2 = 13.64 ,P 〈0.01 ）. The incidence of asthma are superior to those without allergic constitution, intrinsichyperergic idioerasy , family history or smoking in the family members. （ P 〈 0.05 or 0.01 ）. Conclusion： Respiratory syncytial virrus bronchiolitis caused asthma normally, Weft better avoid the related factors and prevent it earlier. And inhaling glucoeorticoid can prevent the asthma in children with respiratory syncytial virrus bronchiolitis.
出处
《河北医学》
CAS
2006年第12期1235-1236,共2页
Hebei Medicine
