摘要
目的探讨CellSlide液基细胞薄层涂片技术(Aud it D iagnostics,爱尔兰)对早期子宫颈癌及癌前病变筛查的可行性。方法以送宫颈细胞标本到本院病理科做检查的患者作为筛查人群(年龄不限),共计3534例,细胞学诊断采用TBS标准,以组织学活检作对照评价Cellslide检查的诊断价值。结果该人群现患病率:不典型鳞状上皮(ASC)为1.9%,低度鳞状上皮内病变(LSIL)为0.2%,符合率100%,高度鳞状上皮内瘤变(HSIL)为0.1%,符合率100%,鳞状细胞癌(SCC)0.03%,符合率100%。结论Cellslide制片效果优良,敏感度和特异度比传统巴氏涂片明显提高,有利于提高病理医生诊断的正确性,在早期子宫颈癌及癌前病变的筛查中发挥有利作用,可以开展为医院防癌筛查的常规项目。
Objective To investigate the feasibility of CellSlide Processor （Audit Diagnostics, Ireland） in screening for early stage cervical carcinoma and precancerous lesion. Methods Cytological examinations were performed in 3534 cervical samples according to TBS standard, Histological examination results were used as gold standard to evaluate the diagnostic value of CellSlide TCT, Results The prevalence for the population was as follows; atypical squamous cells of undetermined significance（ASCUS）1.9%,low grade squamous inner dermal carcinoma lesion （LGSIL） 0.2 %, high grade squamous inner dermal carcinoma lesion （HGSIL） 0.1%, squamous cell carcinoma （SCC） 0.03%. Its diagnostic agreement with histological examination was 100%. Conclusion CellSlide Processor is an effective way of increasing the accuracy of pathological diagnosis with high sensitivity and specificity. It is useful to screening for early stage cervical carcinoma and precancerous lesion and is suitable for routine clinical use in hospitals.
出处
《临床和实验医学杂志》
2007年第1期19-20,共2页
Journal of Clinical and Experimental Medicine
