摘要
目的比较类风湿关节炎(RA)中、西医诊断的特点及关联。方法采集85项RA常见的临床信息,并归为病变部位、量化诊断、症状描述、普遍状况、环境因素5类;从中国期刊网和Medline中分别提取RA中、西医诊察的数据集,分析5类临床信息在中、西医数据集中的出现频数,并进行χ2检验;并基于“同时出现”方法分析中医若干诊察与RA有关生物因素的关联。结果中、西医学对RA的诊断方式具有显著性差异(P<0·01)。与现代医学比较,中医学侧重于诊察RA的症状描述与环境因素,并与RA中的细胞因子、神经内分泌因素具有一定关联。结论对RA症状、环境等因素的诊察是中医辨证论治的重要特色,具有潜在的生物学基础。本研究也为探索中医学的诊断与观察特点,提供了一种方法。
Objective To compare the clinical characteristics of traditional Chinese medicine （TCM） and Western medicine （WM） in diagnosing rheumatoid arthritis （RA）. Methods A total of 85 clinical RA related messages were enacted and classified into 5 sets as pathological locations, quantitative diagnosis, symptomatic descriptions, general status and environment factors. The respective frequency of their presence in the TCM or WM data sets for RA diagnosis collected from MEDLINE and China National Knowledge Infrastructure （CNKI） were analyzed statistically by Chi-square test, and the relationship of some TCM diagnostic factors/conditions with the RA related biological factors was analyzed by co-occurrence-based literature approach of mining. Results There was significant difference between the diagnostic pattern of WM and TCM （P〈0.01）. Compared with that of WM, TCM diagnosis on RA paid more attention to environmental factors and symptomatic descriptions, which showed definite association with the cytokines and neuro-endocrine factors in RA. Conclusion Examination of environmental factors and symptomatic descriptions for RA diagnosis is one of the important characteristics of TCM treatment in accordance to syndrome differentiation, it has its potential biologic basis, A novel approach is proposed for exploring the characteristics of TCM in diagnosis and observation.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2006年第11期988-991,共4页
Chinese Journal of Integrated Traditional and Western Medicine
基金
国家自然科学基金项目(No.90209002
30200365)
国家重点基础研究发展计划(973)项目(No.2003CB517106).
关键词
中、西医学
类风湿关节炎
诊断特点
数据挖掘
Chinese and Western medicine
rheumatoid arthritis
diagnostic characteristics
data-mining
