摘要
探讨99mTc-甲氧基异丁基异腈(MIBI)门控心肌灌注显像所获得的室壁增厚信息在判断冠心病心肌梗死患者中存活心肌的价值。26例确诊的冠心病心肌梗死的男性患者,均在2周内完成12导联心电图(EKG)、99mTc-MIBI静息门控心肌灌注显像、18F-脱氧葡萄糖(FDG)心肌代谢显像,所有病人均接受冠状动脉造影(CAG)。在双核素心肌显像结果提示为缺血存活心肌的心肌节段中,MIBI分布缺损但室壁增厚(WT)正常的心肌节段占双核素显像结果提示为缺血存活心肌节段的68.2%;在双核素心肌显像结果提示为梗死心肌的心肌节段中,MIBl分布缺损且WT异常的心肌节段占双核素显像结果提示为梗死心肌节段的96.8％。静息门控心肌灌注显像所获得的血流灌注和室壁增厚信息与99Tc-MIBI/18F-FDG双核素心肌显像结果具有较高的符合率,故在单纯的心肌血流灌注图像的基础上,结合室壁增厚信息与传统的心肌灌注显像相比有助于检出更多的存活心肌。
To investigate the value of assessing viable myocardium by wall thickening （WT） coming from ^99mTc-MIBI ECG-gated myocardial perfusion imaging （G-MPI） in myocardial infarction, twenty-six patients with myocardial infarction underwent rest ^99mTc-MIBI G-MPI, EKG ^18F-FDG myocardial metabolic imaging and CAG within two weeks. For determining viable myocardium, the segments of myocardium with abnormal MIBI uptake and normal wall thickening （WT） were 68.2% of ischemic viable myocardium demonstrated by ^99mTc-MIBI/^18F-FDG dual isotope tomography. The segments of myocardium with abnormal MIBI uptake and abnormal WT were 96.8% of infarct myocardium demonstrated by dual isotope tomography. Use of wall thickening coming from ^99mTc-MIBI G-MPI may help to select more viable myocardium as compared with conventional myocardial perfusion imaging.
出处
《核技术》
EI
CAS
CSCD
北大核心
2007年第1期61-64,共4页
Nuclear Techniques
基金
上海市卫生局"百人计划"基金资助项目(97BR012)
上海市科委基金资助项目(034119823)
江苏省卫生厅资助项目(H200509)
