摘要
目的：研究知母中的生物碱成分。方法：Sephadex LH-20，Rp-18及硅胶色谱柱分离纯化，根据理化性质和光谱数据鉴定结构。结果：分离鉴定了6个生物碱，分别为aurantiamide acetate（1）、环（酪-亮）二肽（2）、香豆酰基酪胺（3）、N-反式阿魏酰基酪胺（4）、N-顺式阿魏酰基酪胺（5）、烟酸（6）。结论：化合物1～5为首次从百合科植物中分离得到，化合物1～6为首次从知母中分离得到。
Objective： To investigate the alkaloids of Anemarrhena asphodeloides. Method： The compounds were isolated and purified by Sephadex LH -20, Rp-18 and silica gel column chromatography. Their chemical structures were elucidated on the basis of physicochemical properties and spectral data （IR, FAB-MS, ^1H-NMR, and ^13C-NMR）. Result： Six compounds were isolated and identified as ： aurantiamide acetate （ 1 ）, cyclo （Tyr-Leu） （2）, N-p-coumaroyhyramine （3）, N-trans-feruloyhyramine （4）, N-cis-feruloyhyramine （5）, and nicotinic acid （6）, respectively. Conclusion： For the first time, compounds 1-5 were separated from Liliacae plant, and compounds 1-6 were obtained from this plant.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2007年第1期39-41,共3页
China Journal of Chinese Materia Medica
关键词
知母
化学成分
生物碱
Anemarrhena asphodeloides
chemical constituents
alkaloid
