摘要
以40例亚急性期、恢复早期脑血栓形成偏瘫患者为研究对象,随机分成康复治疗组和对照组,观察分析康复训练后即刻及3周后纤溶活性的变化。20例健康老年人作为正常对照。结果为:康复治疗后即刻、康复后3周与康复前相比,组织型纤溶酶原激活物活性分别提高30%和12.6%,组织型纤溶酶原抑制物与激活物比值降低,纤溶活性增高(P<0.01),并高于对照组(P<0.01)。康复训练可部分逆转脑血栓形成患者组织型纤溶酶原激活物及抑制物的异常改变,提高纤溶活性。
The goal of this study was to observe effects of rehabilitation training on fibrinolytic activity in hemiplegic patients with cerebral thrombosis.Forty cerebral thrombosis patients in subacute or early recovery phase were randomly divided into rehabilitation and control groups. Twenty health elderly's people were taken as the control group.Results:Comparing data of an immediate rehabilitation treatment and a delay for three week before rehabilitation to the baseline,the tissue-type plasminogen activator(t-PA)activity increased 30%and 12.6% respectively,plasminogen activator inhibitor(PAI)ratio decreased.and the fibrinolytic activity improved significantly (P<0.01).The above parameters were higher in rehabilitation group than in control group,except PAI/t-PA ratio. Conclusion:The rehabilitation training might partly reverse the blood abnormality of t-PA and PAI activity,and improve fibrinolytic activity .Author's address:(Department of Rehabilitation,Huaiyin Second Hospital,Jiangsu,223002)
出处
《中国康复医学杂志》
CAS
CSCD
1996年第6期251-253,共3页
Chinese Journal of Rehabilitation Medicine
关键词
脑血栓形成
T-PA
康复训练
Cerebral thrombosis
Plasminogen activator of tissue-type
Rehabilitation training