摘要
２０例静脉全麻病人静注异丙酚（ｐｒｏｐｏｆｏｌ）２．５ｍｇ／ｋｇ诱导插入喉罩，评价其临床效果。结果表明，异丙酚诱导起效快，平均２８．６ｓ眼睑反射消失，插管时１８例下颌松弛满意，１７例单次剂量后对喉罩耐受良好，３例因呃逆呛咳等分别追加２０～４０ｍｇ相同药物。诱导后收缩压和舒张压较诱导前明显下降（Ｐ＜０．００１），而插入喉罩并没有引起明显血液动力学改变，诱导中１６例出现呼吸暂停，但几分钟内即恢复自主呼吸。作者认为，异丙酚是插入喉罩较理想的麻醉诱导药，使用中应注意其呼吸及循环抑制作用。
he effect of propofol(2 5mg/kg)was evaluated as an induction agent for insertion of the laryngeal mask airway (LMA)in 20 patients. The results show that propofol induction was rapid(lost eyelid reflex in avarege 28 6s only). 18 patients presented satisfactory mandibular relaxation and 17 patients tolerated LMA well with induction doses except 3 cases receiving additional induction doses (20～40mg) for gaging and coughing. Although SAP and DAP decreased significantly following induction with propofol(P<0 001), no remarkable hemodynamic fluctuation was observed during insertion of LMA. Temporary apnea was found in 16 patients but spontaneous respiration recovered within minutes. Our preliminary results might suggest that propofol is an effective induction agent for LMA insertion but was associated with cardiopulmonary depression.
出处
《临床麻醉学杂志》
CAS
CSCD
北大核心
1996年第5期241-242,共2页
Journal of Clinical Anesthesiology
