摘要
目的观察紫苏梗对正常及肢体缺血再灌注大鼠结肠环形肌条收缩波平均振幅的影响。方法利用肢体缺血再灌注大鼠制备胃肠动力障碍模型。取大鼠结肠环形肌条,置于恒温灌流肌槽内,通过多导生理记录仪记录紫苏梗在结肠环形肌条收缩活动中的效应。结果紫苏梗能升高模型鼠结肠环形肌条收缩波平均振幅,对正常鼠则无明显影响。结论紫苏梗对胃肠动力障碍模型鼠结肠环形肌条收缩运动具有明显的兴奋作用,而对正常鼠结肠收缩运动无兴奋作用。
Objective To study the effect of Perilla frutescens stem on contractile activity of isolated colonic smooth muscle strips in rats. Methods Functional dyspepsia （FD） model was induced in lower limb ischemic reperfusion （LIR） rats. The circular muscle strips of rat colon were suspended. The average contractile amplitude of colonic muscle strips was recorded. Rebaits Perilla frutescens stem increased the average contractile amplitude of colonic muscle strips in FD rats. But it is no use for normal rats. Conclusion The results indicate that Perilla frutescens stem has significant exciting action on contractile activity of isolated colonic smooth muscle strips in FD model rats.
出处
《中国现代医药杂志》
2007年第1期28-29,共2页
Modern Medicine Journal of China
关键词
紫苏梗
胃肠动力
收缩运动
结肠
Perilla frutescens stem Contractile activity Smooth muscle strips Colon
