摘要
目的:探讨中国南方27个民族群体的遗传关系。方法:对27个民族群体CSF1PO、TPOX和TH01基因座基因频率的分布特点进行比较分析,计算群体间的遗传距离,绘制系统发生树。结果:27个民族群体的CSF1PO、TPOX和TH01三个基因座分别以等位基因10、11、12,8、11和7、9的频率最高。蒙自壮族与罗平布依族的遗传距离最小(0.0013),罗平布依族、玉溪傣族间的遗传距离次之(0.0033);浙江畲族和广州汉族遗传距离最大(1.0565)。汉族群体和少数民族群体分别聚为一大族,少数民族群体按“百越”族系和“南蛮”族系及地理位置再聚为6支。结论:相互聚类的民族群体间在历史上有一定族源关系,同时提示群体的基因频率分布与地域呈平行关系。
Objective： To investigate the genetic relation among 27 populations in southern China. Methods： The distribution characteristic of gene frequencies on CSF1PO,TPOX and TH01 loci among 27 populations was compared and analyzed, the Nei＇ s genetic distance calculated and the phylogenetic tree was constructed based on the genetic distance among 27 populations. Results ： The alleles frequencies of 10, lland 12 on CSF1PO, 8 , 11 on TPOX and 7 , 9 on TH01 were the highest among all of 27 populations. The Nei＇s distance between Mengzi Zhuang and Luoping Buyi population was the closest（0. 0013 ）, Luoping Buyi and Yuxi Dai population came to the second（0. 0033） and Jingning She and Guangzhou Han was the farthest （ 1. 0565 ）. The phylogenetic tree shows that Han populations and the minorities populations is a cluster respectively. The minorities populations are classified 6 branches according to ancient ＂Baiyue＂ groups and ＂Nanman＂ groups or geographical position Conclusion：There are relation of historical origin among clustering populations, and the result suggests there are parallel relation between distribution of gene frequencies and geographical region at the same time.
出处
《黔南民族医专学报》
2006年第4期193-197,共5页
Journal of Qiannan Medical College for Nationalities
基金
贵州省教育厅科研基金(黔科教2005222)
黔南民族医专科研基金(QNYZ2005007)资助项目
关键词
STR
遗传距离
系统发生树
群体遗传学
南方群体
中国
short tandem repeat
genetic distance
phylogenetic tree
population genetic
Southern populations
China
