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睾丸支持细胞对肝移植术后急性排斥抑制的实验研究 被引量:1

The effects of infused sertoli cells in liver transplants on the rejection of the transplants: an experimental study with rats
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摘要 原位肝移植术后免疫排斥主要为T细胞及抗体介导的排斥反应。如果能特异性诱导这部分活化T淋巴细胞凋亡,使移植物免受其攻击,即可保护移植物,使其获得免疫豁免。睾丸支持细胞(Sertoli细胞)可持续表达FasL,免疫反应时进入免疫豁免区的活化淋巴细胞高表达Fas抗原,与FasL结合导致淋巴细胞凋亡,从而维持免疫豁免。
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2007年第1期72-73,共2页 Chinese Journal of Hepatology
关键词 肝移植 移植免疫学 塞尔托利细胞 大鼠 Liver transplantation Transplantation immunology SertoliceUs Rats
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参考文献10

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