摘要
从恒河猴孤立的一个新 SV40 种类(SV-IMB ) 的染色体完全被定序并且与其它相比孤立。结果证明整个染色体包含 5246bp，并且 SV-IMB 的 aver 年龄身份作为与另外的 SV40 相比是 98.1% 孤立。它的规章的区域由完全的 enhancer 和有缺点的 e enhancer 组成。氨基酸变化在大 T 抗原(标签) 和 VP1 区域发生了到某程度。调查结果证明 SV-IMB 是新 SV40 孤立。关键词 SV40 - 标签 - 规章的区域 CLC 数字 S852.65 基础条款：国家自然科学成立(30570081 )
The genome of a new SV40 strain（SV-IMB）isolated from a rhesus monkey was completely sequenced and compared with other isolates. The results showed that the whole genome contains 5246bp, and the average identity of SV-IMB was 98.1% as compared to other SV40 isolates. Its regulatory region is composed of a complete enhancer and a defective enhancer. Amino acid changes occurred to some ex- tent in both the large T antigen （T-Ag） and VP1 region. The findings demonstrate that the SV-IMB is a new SV40 isolate.
出处
《中国病毒学》
CSCD
2007年第1期41-45,共5页
Virologica Sinica
基金
National Nature Science Founds(30570081)
