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症状性颅内外动脉狭窄内支架成形术前后脑灌注CT成像的变化以及与临床疗效的关系 被引量:14

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摘要 目的探讨颅内外动脉狭窄内支架成形术前后脑灌注CT成像的变化以及与临床疗效之间的关系。方法本研究纳入12例颅内外动脉狭窄的患者,其中表现为前、后循环TIA9例,颈内动脉系统有梗死病灶3例。所有患者均给予狭窄动脉行内支架成形术,并于支架术前、术后48h以及6~12个月的随访期内行头CT灌注成像检查。结果支架术前9例前、后循环TIA患者,灌注成像表现为7例rCBF下降,2例rCBF正常;3例rCBV增高、6例rCBV正常;8例TTP、MTT延长,1例TTP、MTT正常。术后6~12个月,7例rCBF正常。2例rCBF下降;6例rCBV正常,2例增高,1例轻度增高;5例TTP、MTT正常,4例TTP、MTT轻度延长。在6~12个月随访期内,有2例出现TIA,均出现支架后的再狭窄,灌注CT表现为rCBF下降、rCBV增高,TTP、MTT延长。3例行颈内动脉支架的脑梗死患者,支架术前3例rCBF下降;1例rCBV轻度增高,1例rCBV下降,另1例rCBV正常。术后6~12个月,2例rCBF正常,1例rCBF轻度下降;1例rCBV正常,2例rCBV轻度增高;3例TTP、MTT仍延长。3例术前NIHSS评分分别为7、5、6,术后随访期间转为3、3、2。其中1例显示支架后再狭窄,灌注CT表现为rCBF轻度下降,rCBV轻度增高。结论灌注CT成像各指标的转归与临床症状和体征的改善具有密切的相关性,灌注CT成像可作为评价临床症状转归的一个客观指标。
出处 《中国神经精神疾病杂志》 CAS CSCD 北大核心 2007年第1期51-53,共3页 Chinese Journal of Nervous and Mental Diseases
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