摘要
目的：探讨急性阑尾炎围手术期甲状腺激素水平的变化规律及其临床意义。方法：选择82例急性阑尾炎患者，分别于手术前、手术后1、3、5、7、14d取空腹静脉血，利用放射免疫分析检测FT3、FT4、T3、T4、rT3及TSH水平，同时分析甲状腺激素水平与临床病理分型、并发症的关系。结果：本文患者手术前均存在不同程度的低FT3、FT4、T3、T4血症和高rT3血症，且以坏疽性和穿孔性阑尾炎最明显。这种现象均于术后（5．7）d恢复正常，但当出现感染性并发症时血清FT3、FT4、T3、T4持续低下，而临床治愈后则恢复正常水平。结论：急性阑尾炎患者甲状腺内分泌功能均受到不同程度的抑制，围手术期动态观察FT3、FT4、T3、T4、rT3血液激素水平，有利于判断病情轻重、临床病理分型和感染性并发症的存在，有利于临床治疗方案的制定。
Objective To investigate the clinical significance of perioperative changes of serum levels of thyroid hormones in pa- tients with acute appendicitis. Methods Serum FT3, FT4, T3 , T4, rT3 , TSH levels were measured with RIA in 82 patients with acute appendicitis during the peri - operative period （ before operation and 1,3, 5,7, 14 days after operation）. Results Before operation, serum levels of FT3 , FT4, T3 , T4 were significantly lower and rT3 levels were significantly higher than those in controls. The levels returned to approximately normal in about 5 - 7 days post -operatively. However, in 5 patients complicated with abdominal or incisional abscess formation, the levels remained abnormal until rosolution of the inflammation. Conclusion Thyroid function inhibi- ted in patients with acute appendicitis, especially in the severe cases. Delayed recovery of thyroid function postoperatively occurred in patients with complications.
出处
《放射免疫学杂志》
CAS
2007年第1期3-5,共3页
Journal of Radioimmanology
关键词
阑尾炎
甲状腺素
appendicitis, thyroid hormone
