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美洛西林钠在木糖醇输液中的配伍稳定性考察 被引量:7

Study on the stability of compatibility of mezlocillin sodium in 5% xylitol injection
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摘要 目的:考察不同温度(25℃、37℃)下6h内,美洛西林钠与木糖醇的配伍稳定性。方法:用紫外分光光度法测定配伍液中关洛西林含量,并观察外观、pH值的变化。结果:美洛西林钠与木糖醇输液配伍后6 h内,其外观,pH值以及含量均无明显变化。结论:美洛西林在上述条件下可以与木糖醇输液配伍使用。 Objectlve: To study the stability of compatibility of mezlocillin sodium in 5% xylitol injection at different temperature (25 ℃, 37 ℃) winthin six hours. Methods: The content of mezlocillin was determined by UV-spectrophotometry, and the appearance of the solution was observed and its pH value was tested. Results: There were no significant changes in appearance, pH value and content of the mixed solution winthin six hours. Conclusion: Mezlocillin sodium mixed with 5% xylitol injection can be used under above-mentioned conditions winthin six hours
出处 《药学实践杂志》 CAS 2007年第1期21-22,共2页 Journal of Pharmaceutical Practice
关键词 美洛西林钠 木糖醇注射液 配伍 稳定性 紫外分光光度法 mezlocillin sodium xylitol injection compatibility stability UV-spectrophometry
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