摘要
目的观察老年高危患者围手术期应用β1受体阻滞剂的疗效。方法术前数天或数周口服美托洛尔50-100mg/d,将静息心率逐渐控制在5565次/min。术中以平均1mg/min的速度缓慢静推1支5mg美托洛尔,之后观察5min,再给第2支、第3支,使心率达标。结果应用β1受体阻滞剂组的心力衰竭、心律失常、心血管性死亡、非致死性心梗的发生率明显低于未接受β1受体阻滞剂组,差别有统计学意义。结论老年高危患者围手术期适合应用β1受体阻滞剂。
Objective To research effects of β1-receptor blocker on the gerontal high risk patients perioperatively. Methods The patients took metoprolol 50100 mg daily orally before operation weeks or months for decreasing gradually resting heart rate to 5565 times per minute. During operation, the patients were given intravenous injection of metoprolol 5 mg at an average speed of 1 mg per minute. After five minutes,anther 5 mg or 10 mg metorpolol were administered to control the heart rates. Results The incidence of cardiac failure, arrhythmia,cardiovascular death and nonfatal cardiac infarction in the patients with application of β1- receptor blocker were much lower thah that of control group. The difference had statistical significance. Conclusions Administration of β1 -receptor blocker is suitable for those gerontal heavy patients perioperative.
出处
《实用全科医学》
2007年第1期13-14,共2页
Applied Journal Of General Practice
