摘要
目的:了解腹腔镜胆囊切除术对胰高血糖素和C肽的影响。方法:20例择期在全麻下行胆囊切除术的病人,随机分为腹腔镜胆囊切除术组(LC组,n=10)和开腹胆囊切除术组(OC组,n=10)。分别于术前、气(开)腹后10min、术毕10min取血样,用放免法测定血浆胰高血糖素和C肽。结果:两组的胰高血糖素在气(开)腹后10min和术毕10min都高于术前,差异有统计学意义(P<0.05),其中OC组开腹后和LC组气腹后相比,升高明显(P<0.05)。LC组气腹后和术毕C肽水平均高于术前,术毕增高明显(P<0.05);和术前相比,OC组开腹后C肽降低(P<0.05),术毕升高。OC组开腹后和LC组气腹后相比差异有统计学意义。结论:LC对胰高血糖素和C肽的影响要明显弱于OC。
Objective. To study the influence of laparoscopic choleeystectomy on Glucagon and C - peptide. Method 20 patients underwent elective choleeysteetomy were randomly divided into laparoscopie choleeystectomy group （LC group, n = 10） and open eholeeysteetomy group （OC group, n = 10）. Blood samples were obtained before operation, 10 min after pneumoperitoneum with carbon dioxide or laparotomy and 10 min after operation. The plasmie levels of C - peptide and Glueagon were measured with radio - immunoassay technique. Results Compared with preoperative values, signifieandy increased Glueagon were observed in both groups （ P 〈 0.05 ）, but the value of Glucagon after laparotomy in OC group were much higher than that in LC group after pneumoperitoneun（ P 〈 0.05 ）. The plasmie C - peptide levels after pneumopefitoneum and after operation were higher tban those before operation in LC group and the level after operation significantly increased（ P 〈 0.05）. Compared witb preoperation, C - peptide level reduced after laparotomy（ P 〈 0.05 ） and increased after operation in OC group. The level of C - peptide in LC group after pneumoperitoneum has signifieant difference with that in OC group after laparotomy. Conclusion LC has a weaker impact on C - peptide and Glueagon compared with OC.
出处
《吉林医学》
CAS
2007年第1期45-46,共2页
Jilin Medical Journal
