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心房颤动离子通道重构的研究进展 被引量：1

Progress of Ion Channel Remodeting in Atrial Fibrillation
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摘要 心房颤动是临床上最常见的心律失常,目前国内外学者研究认为,心房电重构在心房颤动发生和维持中起主要作用,而心房电重构主要由离子通道重构引起,本文对此进行综述。 Atrial fibrillation is a common cardiac arrhythmia. Now many advanced researchers report that atrial electrical remodeling is the most important factor in its occurrence and maintenance, which is mainly caused by ion channel remodeling. This article reviews these all.
作者 庞伦祥 何劲松 刘钧超
机构地区 广西中医学院附属瑞康医院心内科
出处 《医学综述》 2007年第2期94-95,147,共3页 Medical Recapitulate
关键词 心房颤动 电重构 离子通道 Atrial fibrillation Electrical remodeling Ion channel
分类号 R541.75 [医药卫生—心血管疾病]
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参考文献22

  • 1Wiffels MC, Kirchhof CJ, Dorland JD, et al. Atrial fibrillation beyets atrial fibrillation: a study in awake chronically instrumented goats [ J ].Circulation, 1995,92(7) : 1954-1968.
  • 2Nattel S. News ideas about fibrillation 50 years on[J]. Nature, 2002,415(6868) :219-226.
  • 3Yue L, Melnyk P, Caspo R, et al. Molecular mechanisms underlying ionic remodeling in a dog model of atrial fibrillation[J]. Circ Res,1999,84(7) :776-784.
  • 4Lai LP,Su MJ, Lin JL, et al. Dower-rcgalation of L-type calcium channel and sarecopasmic reticular Ca^2 + -ATPasc mBNA in human atrial fibrillation without singnificant change in the mBNA of ryanodine receptor,calsequestrin and phospholamban: an insight into the mechanish of atrial electrical remodeling[ J]. J Am Coll Cardiol, 1999,33 (5) : 1231-1237.
  • 5Grammer JB, Bosch RF, Kuhlkam PV, et al. Molecular and electrophysiological evidence for "remodeling" of the L-type Ca^2+ channel in persistent atrial fibrillation in huraans [ J]. Z Kardiol, 2000, 89 (Suppl 4) : Ⅳ 23-29.
  • 6张薇,张学义,钟明,张供,卞继峰,张运.心房颤动电重构心房肌Ca^(2+)调控蛋白异常与解剖学改变关系的研究[J].中华心律失常学杂志,2002,6(2):93-96. 被引量：5
  • 7张建成,黄从新,邓玉莲,施作霖,许春萱,林立芳,胡锡衷.心房颤动患者L型钙通道电流改变的分子基础[J].中华心血管病杂志,2002,30(8):460-463. 被引量：15
  • 8Gaspo R, Bosch RF, Bou-Abboud E, et al. Taehyeardia-induced changes in Na^+ current in a chronic dog model of atrial fibrillation[J] .Citc Res, 1997,81(6) : 1045-1052.
  • 9Tieleman RG, De-Langen C, Gelder IC, et al. Verapamil reduces tachycardior-induced electrical remodeling of the atrial [ J]. Circulation,1997,95(7) : 1945-1953.
  • 10Van Wagoner DR,Pond AL,MeCartry PM,et al.Outward K+ current densities and KV1.5 expression are reduced inchronic human altrial fibrillation[ J]. Circ Res, 1997,80(6) :772-781.

二级参考文献84

  • 1Wiffels MCEF, Kirchhof CJHJ, Dorland R, et al. AF begets AF: a study in awake chronically instrumented goats. Circulation, 1995, 92:1954-1968.
  • 2Bosch RF, Zeng X, Grammer YB, et al. Ionic mechanisms of electrical remodeling in human atrial fibrillation. Cardiovasc Res, 1999,44:121-131.
  • 3Yue L, Melnyk P, Gaspo R,et al. Molecular mechanisms underlying ionic remodeling in a dog model of atrial fibrillation. Circ Res, 1999,84:776-784.
  • 4Lai LP, Su MJ, Lin JL, et al. Down-regulation of L-type calcium channel and sarcopasmic reticular Ca2+-ATPase mRNA in Human atrial fibrillation without significant change in the mRNA of ryanodine receptor, calsequestrin and phospholamban-an insight into the mechanism of atrial electrical remodeling. J Am Coll Cardiol,1999,33:1231-1237.
  • 5Brundel BJJM, Van Gelder IC, Henning RH, et al. Gene expression of proteins influencing calcium homeostasis in patients with persistent and paroxysmal atrial fibrillation. Cardiovascular Research, 1999,42:443-454.
  • 6Cheng TH, Lee FY, Wei J, et al. Comparison of calcium-current in isolated atrial myocytes from failing and nonfailing human hearts. Mol Cell Biochem, 1996,157:157-162.
  • 7Boixel C, Gonzalez W, Louedec L, et al. Mechanisms of L-type Ca(2+) current down-regulation in rat atrial myocytes during heart failure. Circ Res, 2001,89:607-613.
  • 8Li GR, Nattel S. Properties of human atrial ICa at physiological temperatures and relevance to action potential[J]. Am J Physiol, 1997, 272(1): H227-H235.
  • 9Yue L, Feng J, Gaspo R, et al. Ionic remodeling underlying action potential changes in a canine model of atrial fibrillation [J]. Circ Res, 1997, 81(4): 512-515.
  • 10Bosch RF, Zeng X, Grammer JB, et al. Ionic mechanisms of electrical remodeling in human atrial fibrillation[J]. Cardiovasc Res, 1999, 44(1): 121-131.

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医学综述
2007年 第2期

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