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调强放疗在非小细胞肺癌中的应用 被引量：5

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摘要 调强放疗（intensity modulated radiation therapy,IMRT）是在传统的三维适形放疗（3-dimensional conformal radiation thempy，3DCRT）基础上，随着计算机发展和放疗设备改进而产生的更为先进的放疗技术。相比于3DCRT，IMRT可形成更好的适形于肿瘤的物理剂量分布，从而能提高肿瘤靶区的剂量和更好的保护正常组织。近年来，IMRT已越来越多的应用于临床中：在鼻咽癌和前列腺癌上，IMRT临床研究初步结果显示出其良好的临床获益；但在肺部肿瘤中由于种种不确定因素的存在，IMRT用于临床需要慎重对待。
作者 朱正飞 傅小龙
机构地区 复旦大学附属肿瘤医院放疗科
出处 《中华放射肿瘤学杂志》 CSCD 北大核心 2007年第1期58-61,共4页 Chinese Journal of Radiation Oncology
关键词 调强放疗 非小细胞肺癌 三维适形放疗 物理剂量分布 IMRT 临床研究 肿瘤靶区 3DCRT
分类号 R686 [医药卫生—骨科学]
  • 相关文献

参考文献21

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  • 2Marnitz S,Stuschke M,Bohsung J,et al.IntraindⅣidual comparison of conventional three-dimensional radiotherapy and intensity modulated radiotherapy in the therapy of locally advanced non-small cell lung cancer a planning study.Strahlenther Onkol,2002,178:651-658.
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同被引文献56

  • 1韩勇,徐晖,王云杰,王安辉.慢性阻塞性肺疾病与肺癌危险性关系的探讨[J].中国肿瘤临床,2005,32(8):421-423. 被引量：20
  • 2林少俊,陈传本,韩露,郑葳,陈梅,潘建基.鼻咽癌调强放射治疗230例初步结果[J].福建医科大学学报,2007,41(1):66-70. 被引量：61
  • 3彭齐荣,张罗生,张红梅,贾彦征,段宇新,高兴旺.43例鼻咽癌的调强适形放射治疗体会[J].现代肿瘤医学,2007,15(3):320-322. 被引量：4
  • 4余光伟,毛新建.调强技术治疗非小细胞肺癌可能性分析及剂量评估[J].中华放射医学与防护杂志,2007,27(2):167-169. 被引量：7
  • 5Seppenwoolde Y, Muller SH, Theuws JC, et al. Radiation dose-effect relations and local recovery in perfusion for patients with non- small cell lung cancer. Int J Radiat Oncol Biol Phys, 2000, 47(3) : 681-690.
  • 6Claude L, Perol D, Ginestet C, et al. A prospective study on radiation pneumonitis following conformal radiatiantherapy in non- small-cell-lung cancer: clinical and dosimetric factors analysis. Radiat Oncol, 2004, 71(2) : 175-181.
  • 7Kim TH, Cho KH, Pyo HR, et al. Dose-volumetric parameters for predicting severe radiation pneumonitis after three-dimensional conformal radiation therapy for lung cancer. Radiology, 2005, 235 (1): 208-215.
  • 8Vivek Mehta. Radiation pneumonitis and pulmonary fibrosis in non- small cell lung cancer: pulmonary function, predicting, and prevention. Int J Radiat Oncol Biol Phys, 2005, 63(1): 5-24.
  • 9Liu HH, Wang X, Dong L, et al. Feasibility of sparing lung and other thoracic structures with Intensity-Modulated Radiotherapy for non-small cell lung cancer. Int J Radiat Oncol Biol Phys, 2004, 58 (4) : 1268-1279.
  • 10Abratt RP, Willcox PA, Smith JA. Lung cancer in patients with borderline lung functions: zonal lung Perfusion scans at presentation and lung function after high dose irradiation. Radiother Oncol, 1990, 19(4) : 317-322.

引证文献5

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中华放射肿瘤学杂志
2007年 第1期

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