摘要
生物芯片的研发重心正由被动式芯片转向主动式生物芯片领域,电化学分析方法在主动式生物芯片的研发中已展现出巨大的技术优势。纳米材料具有巨大的比表面积和界面,对外部环境的变化十分敏感,温度、光、湿度和气氛的变化均会引起表面或界面粒子价态或电子传递的改变,且响应快、灵敏度高,所以,纳米材料是制备高效生物传感器和生物芯片最佳固定材料之一。以纳米复合材料构筑仿生膜,既有利于蛋白质(酶)生物活性的保持,又有利于发挥纳米材料和蛋白质相互作用过程中电子传递响应快、检测灵敏度高的优势,因此,电分析和纳米技术必将在生物芯片的发展中有所作为。
The research hotspot of biochip is transferring from passive chip to initiative chip, and the electroanalysis technology shows prominent technology advantage in this process. Nano-materials are very sensitive to the change of environment for their huge interface. All of temperature, light, humidity or ambience Variety will change electron transfer state and nano-materials interface, with rapid and sensitive response, which indicates the nanomaterial are one of the best fixed materials for making efficient biosensor and biochip. The biomimetic films made from nanomaterial are propitious to both the bioactivity maintenance of protein （anzyme） and the superiority exertion of rapid electron transform and high sensitivity in the interaction between nanomaterial and protein. Results show there will be great application for nanotechnology and electralysis in biochip development.
出处
《传感器与微系统》
CSCD
北大核心
2007年第2期8-10,14,共4页
Transducer and Microsystem Technologies
关键词
生物芯片
电分析
纳米技术
biochip
electranalysis
nanotechnology
