期刊文献+

兔铅中毒后肝细胞超微结构的变化

CHANGES OF ULTRASTRUCTURE IN RABBITS LIVER CELLS INDUCED BY LEAD ACETATE
下载PDF
导出
摘要 在兔腹腔内注射醋酸铅造成肝细胞损伤后,电镜下观察肝细胞超微结构的变化表现在:1)细胞核——伴随肝细胞内细胞核的畸形,常染色质减少,异染色质增多.2)细胞质——线粒体数量减少或增加,体积大小不定兼畸形,线粒体嵴和膜变异.内质网的膜腔扩大,RER膜上的核糖体颗粒减少.3)细胞膜——细胞间的交界面呈波浪型交措并加宽. The damage of rabbits liver cells was induced by intraperitioneal injection of lead acetate.The changes of ultrastructure in hepatocytes were observed under electron microscope.The effects of lead acetate on hepatocytes included following basic abnormalities:1)the characteristic features of the nucleus are irregulat in shape,decreasing of euchromatin,increasing of hete rochromutin.2)the characteristic features of cytoplasm are as follows.The mitochondria increase of decrease in number and size,they are irregular in shape with some variation in cristal pattern.Endoplasmic reticulum(ER)increase in the lumina,de tachment of some ribosmes from the membraneous component of rough endoplasmic reticulum(RER).3)the characterristic features of the cell memberane showed that plasmalemma connecting between the adjacent hepatoma cells may be wavelike or interdigitated and became width.
出处 《广西师范大学学报(自然科学版)》 CAS 1996年第1期82-85,共4页 Journal of Guangxi Normal University:Natural Science Edition
基金 广西青年科学基金资助课题
关键词 醋酸铅 肝细胞 超微结构 铅中毒 lead acetate hepatocyte ultrastrucure rabbit
  • 相关文献

参考文献2

  • 1杭振镳等.电子显微镜术在临床医学的应用[M]重庆出版社,1988.
  • 2王莹,孙维生,魏少征.化工职业中毒临床手册[M]人民卫生出版社,1982.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部