摘要
目的探讨山豆根中毒的脑 MRI 表现。方法对临床诊断为山豆根中毒的4例患者采用1.5 TMR 仪行常规MR(T_1WI 和 T_2WI)和扩散加权成像(DWI)检查。结果 4例小脑齿状核均呈对称性小片状长 T_1、T_2信号改变,DWI 呈等信号,表观扩散系数(ADC)图信号升高,其中1例同时累及双侧脑干背侧和丘脑,1例症状较重患儿伴有双侧基底节区对称性片状长 T_1、T_1信号改变,DWI呈高信号,ADC 图信号减低。2例复查显示齿状核异常信号消失,1例基底节受累病灶趋向囊性变(长 T_1、T_2信号),DWI 显示为低信号。结论山豆根中毒可以特异性累及齿状核和豆状核,MRI 和DWI 有利于早期诊断、鉴别诊断和评估预后。
Objective To discuss the MRI features of sophorae subprostrate intoxication. Methods Four cases with sophorae subprostrate intoxication underwent conventional MRI and diffusion-weighted imaging （DWI） with a 1.5 T MR system. Results In four cases, all cerebellar dentate nuclei showed symmetric patchy hyper-inteusity on T2 weighted images and iso-inteusity on diffusion-weighted images as well as hyper-intensity on ADC maps. The bilateral dorsum of the brain stem and thalamus were involved in one case. Symmetric long Tt and T2 signals and high DWI signals with low ADC values in bilateral basal ganglia area were demonstrated in one case with severe symptoms. After treatment, repeated MR images in two cases showed the abnormal signals of dentate nucleus disappeared, and the lesions of basal ganglia area in one case tended to be cystic with longer T1 and T2 signals and low DWI signals. Conclusion It is specific for intoxication of sophorae subprostrate to affect the dentate nuclei and lentiform nuclei. MRI and DWI is helpful for the early diagnosis,differential diagnosis and prognosis evaluation of this disease.
出处
《中华放射学杂志》
CAS
CSCD
北大核心
2007年第2期140-142,共3页
Chinese Journal of Radiology
关键词
山豆根
中毒
磁共振成像
Sophorae subprostrate
Poisoning
Magnetic resonance imaging
