摘要
目的探讨甲状腺机能亢进症患者131Ⅰ治疗前后骨密度的变化情况．方法54名甲亢患者在131Ⅰ治疗和治疗后3个月，6个月分别检测血甲状腺激素．sTSH测定其骨密度．结果131Ⅰ治疗前55．56％患者骨密度减少；治疗后3个月患者骨密度与治疗前无差异。而治疗后6个月有效组和痊愈组患者骨密度明显上升。无效组和甲低组与治疗前无变化，结论应用131Ⅰ治疗甲亢可以使患者骨密度在短时间（6个月）较好的恢复；治疗后甲低患者的骨密度不能恢复，因此。治疗时要尽量减少甲低的发生．一旦出现，应及时培予甲状腺素替代治疗。
Objective To investigate the changes of bone metabolism in patients with hyperthyroidism before and after 131 Ⅰ therapy. Methods The serum levels of FT3 FT4, sTSH and bone mineral density（BMD） of 54 patients with hyperthyroidism were measured before and after 131 Ⅰ therapy 3 month and 6month. Results 55.56% patients with hyperthyroidism were discovered incidence of bone mineral density diminution; there was no significantly improved in patients .with hyperthyroidism before and after 131 Ⅰ therapy 3 month, however, there was significantly improved after 131 Ⅰ therapy 6 month in those patients who have been cured or have effects, and no change in those who have no effect or hypothyroidism. Conclusion BMD of hyperthyroidism patients can resume to normal in a short period of time（6 month） after using 131 Ⅰ therapy; hypothyroidism patients after 131 Ⅰ therapy can not resume, so we should avoid the incident of hypothyroidism as possible, and thyroxin substitute therapy if only hypothyroidism occur.
出处
《北华大学学报（自然科学版）》
CAS
2007年第1期68-69,共2页
Journal of Beihua University（Natural Science）
