摘要
抑郁症有其生物学基础,如脑内神经递质和神经内分泌功能的改变,下丘脑-垂体-肾上腺(HPA)轴负反馈失调和神经免疫异常等。近年来,抗抑郁症类药物随着抑郁症病理生理学研究的深入而逐渐发展。本文对抗抑郁药临床应用等进行了综述。
change Depression is based on some biological theories, such as of neurotransmitter and hormone secretion in brain tissue, dysfuction of hypothalamic - pituitary - adrenal systerm negative - feedback and neuroimmunologic abnormality et al. Recently, followed study of depressive pathophysiology, pharmacological management of depression has made some progeress. In this review, biological theories of depression and clinical usage of antidepressant are discussed.
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2007年第1期54-57,共4页
The Chinese Journal of Clinical Pharmacology
