5[1]Shen ZX, Chen G Q, NiJ H et al. Use of arsenic tri oxide (As2 O3) in the treatment of acute promyelocytic leukemia (APl): Clinical efficacy and pharmacokinetics in relapsed patients. Blood, 1997, 89:3354
6[2]Puccetti E, Guller S, Orleth A et al. Bcr-Abl mediates arsenic trioxide-induced apoptosis independently of its aberrant kinase activity. Cancer Res, 2000, 60:3409
7[3]Perkins C, Kim C N, Fang G F et al. Arsenic induces apoptosis of multdrug-resistance human myeloid leuke mia cells that express Bcr-Abl or overexpress MDR, MRP, Bcl-2, or Bcl-XL. Blood, 2000, 95:1014
8[4]Uslu R, Sanli U A, Sezgin C etal. Arsenic trioxide me diated cytotoxicity and apoptosis in prostate and ovarian carcinoma cell lines. Clin Cancer Res, 2000, 6: 4957
9[5]Grad J M, Bahlis N J, Reis I et al. Ascorbic acid enhances arsenic trioxide-induced cytotoxicity in multiple myeloma cells. Blood, 2001, 98:805
10[6]Alemany M, Levin J. The effects of arsenic trioxide (As2O3) on human megakaryocytic leukemia cell lines. With a comparison of its effects on other cell lineages. Leuk Lymphoma, 2000, 38:153
